Treatment of Opioid Use Disorder Overdose Prevention

Research has shown that methadone, buprenorphine, and naltrexone can reduce opioid use and other negative health outcomes. These symptoms can include feeling sick, stomach cramps, muscle spasms, heart pounding, aches and pain, or sleep problems.18 Lofexidine is not used for long-term treatment of opioid use disorder. When people start opioid use disorder treatment, they usually